A few weeks back, Donny Mack of DotNetJunkies.com wrote an intriguing tutorial on enabling HTTP Compression in IIS 6.0.  My company's web host, ORCSWeb, just did this for its shared server customers, and I won't say the performance difference is like night-and-day, but it does serve content markedly faster....some 72% by my estimates.

If you run ASP.NET on a server you control, read Donny's article and give this serious consideration.  It's worth it, and it's the real deal.

The HTTP compression, coupled with server-side caching, will literally blow your socks off for your web apps.