Unit Testing, Agile Development, Leadership & .NET - By Roy Osherove
You shouldn't do this if you do web development on your machine.
I had to remove this setting as it quickly overloads the 10 connection limit of IIS for Windows XP Professional on my dev workstation. This can cause odd little bugs within IE of certain elements of a page not loading. Worse, trying to do cross-browser dev often results in "too many connections" server errors.