IIS and Skype
I couldn't browse to the default website running on an XP SP2 machine earlier today, which was odd, since it worked yesterday, and I hadn't done anything since but reboot. Event Viewer said that IIS couldn't bind instance 1. w3svc/1 was configured to run on port 80. I thought at first that it might be something to do with the new firewall in XP SP2 blocking IIS, but that seemed odd and besides I couldn't find any mention of IIS in the firewall UI.
Then I thought of trying Port Reporter to see what was listening on port 80, and I quickly discovered that it wasn't IIS, but Skype. I dug into the Skype UI and found that "Use port 80 as an alternative for incoming connections" was checked. Clearing this made the problem go away.
This is quite odd because I've been running Skype and IIS 5.1 on another XP machine for months without problems. I just checked and "port 80" was selected on that machine's Skype too.