The type 'System.Web.UI.ScriptManager' is ambiguous: it could come from assembly...
If you are trying to migrate an old application to work with the framework 3.5, you are using ajax, and get the following error...
The type 'System.Web.UI.ScriptManager' is ambiguous: it could come from assembly 'C:\WINDOWS\assembly\GAC_MSIL\System.Web.Extensions\1.0.61025.0__31bf3856ad364e35\System.Web.Extensions.dll' or from assembly 'C:\WINDOWS\assembly\GAC_MSIL\System.Web.Extensions\3.5.0.0__31bf3856ad364e35\System.Web.Extensions.dll'. Please specify the assembly explicitly in the type name.
You need to delete all your \bin files and rebuild the application.