Subversion 1.0 + VS.NET
So, Scoble linked to a post about subversion going 1.0 today. What you may not realize is not only does subversion run completely on its own on any Windows machine (yes, no Apache is needed unless you want WebDAV support), but it is fairly easy to get up and running, comes with great documentation, and there is a VS.NET add-in if you just can't wait to ditch SourceSafe, but want to do it from the safety of VS.NET.
Other subversion tools that you might find useful when killing off all your SourceSafe repositories:
RapidSVN (GUI client)
http://rapidsvn.tigris.org/Subway (SCC provider)
http://nidaros.homedns.org/subway/TortoiseSVN (Shell Extension)
http://tortoisesvn.tigris.org/
And, when you are doing multi-project ASP.NET apps and want to have all your project folders under the same directory to ease synchronization, make sure to take a look at this article for a workaround to the pesky “always create in inetpub“ issues that VS.NET has.